StateZero Platform
Virtual CRISPR engine for in-silico target prioritization — simulating perturbation outcomes across multi-omic latent spaces before wet-lab validation.
Building the infrastructure for scarless regeneration.
AI/ML Architect and Founder specializing in multi-omic latent alignment, automated DBTL screening cycles, and Nextflow pipeline orchestration.
My Vision
Making Biology Engineerable
Drug discovery pipelines now rely on experimental work and manual target identification, success rate <10%.
My goal is to completely automate the biological Design-Build-Test-Learn cycle.
This requires a foundational data layer. My current work focuses on mapping multi-omic (transcriptomic and epigenomic) shifts into a unified computational latent space. By converting it to math coordinates, we can systematically model and execute virtual CRISPR perturbations.
This allows us to mathematically engineer cell states and accelerate the efficiency of therapeutic target identification.
News & Traction
Updates
- Started building the failure database oncology never kept.[linkedin article][git repo]
- Won 2nd place at the Nebius & Clwabio Hackathon — Cancer Target Objection and Prioritization Track.[linkedin article][git repo]
- Working on BioChemCPA — redesigning ChemCPA for embracing Biological Entities.[linkedin article][git repo]
- GRN Consensus and reliable benchmarking.[linkedin article][git repo]
- Updated and expanded StateZero platform — metabolomics, Reactome mapping, growth factors, and diffusion models for drug candidate selection.
- Dissected SCENIC+ pipeline and extracted standalone GRN-inference core.[grn-core-source - git repo][article]
- Initial concept for Cell Atlas — interactive cell-state transition mockup.[CellAtlas]
- Started architecting StateZero Labs platform for developing regenerative therapies.[StateZero]
- Built advanced segmentation CV pipeline for medical images — analysis of 20k+ murine ear images.
- Deployed automated SAM-based workflow for medical image analysis for the lab, reducing processing time 10×.[sam - git repo]
- Built cellular automata explaining origin of protein life — from entropy and initial gas state to template-directed self-assemblies. All personal questions on the origin of life answered; satisfied my curiosity.[article]
- Started Undergraduate Research Fellow position at the Laboratory for Regenerative Medicine, Gdańsk Tech.
About
About Me
AI/ML Architect and Founder specializing in multi-omic latent alignment, automated DBTL screening cycles, and Nextflow pipeline orchestration.
I build Bio-MLOps infrastructure at StateZero Labs — systems that connect single-cell transcriptomics, virtual CRISPR screening, and chemical latent-space alignment into reproducible pipelines for target identification and cellular regeneration.
Core Infrastructure Stack
NextflowDockerPythonPyTorchScanpySCENICReactome
Current Deployment
Currently at the Max Delbrück Center (Bunina Lab), working on transcriptomics, GRNs and perturbation algorithms.
Experience
Roles
- Jun 2026 — Oct 2026
Visiting Computational Researcher
Bunina Lab, Max Delbrück Center · Berlin, DE
- Oct 2025 — Present
Undergraduate Research Fellow
Laboratory for Regenerative Medicine, Gdańsk University of Technology
Research
Research & Publications
BioChemCPA: Expanding ChemCPA Model to Biological Entities
Abramau, P.
Preprint · July 2026 · With apart research, CIC Secret Loyalties Hackathon
Linking CRISPR to Chemical Space — StateZero Labs Engine
Abramau, P.
2026 — currently in work
Investigating Mouse Ear Pinna as Regeneration Model
Sachadyn P., Abramau P., et al.
Preprint · 2026 — coming soon
Education
Academic Background
- Jun — Oct 2026
Internship — Computational Biology
Max Delbrück Center for Molecular Medicine
- Feb — Jun 2026
B.Sc. Erasmus+ Biotechnology & AI
University of Barcelona
- 2024 — 2028
B.Sc. Biotechnology
Gdańsk University of Technology
Projects / Pre-prints
Research Output
Automated Metabolic Parsing
LLM-driven pipeline integration for Reactome and GSEA — extracting structured pathway hypotheses from unstructured literature and experimental readouts.
Contact
Currently securing a remote Autumn infrastructure sprint.